Albacete -Real Madrid goalkeeper Iker Casillas will make his 151st international appearance as Spain look to seal their place in next year's World Cup at home to Georgia in Albacete on Tuesday.
The world champions need just a point from the game to ensure they top Group I and book their tickets to Brazil next year.
Casillas' inclusion is a surprising one as he had been dropped by Spain boss Vicente del Bosque in favour of Victor Valdes for Friday's 2-1 win over Belarus with the 62-year-old citing Casillas' lack of first-team action this season at club level as the reason for the change.
Del Bosque makes six changes in all from the side that started in Palma on Friday.
Sevilla left-back Alberto Moreno is handed his international debut ahead of Arsenal's Nacho Monreal.
And Juanfran, Andres Iniesta and the Manchester City duo of Jesus Navas and Alvaro Negredo are also included at the expense of Alvaro Arbeloa, Cesc Fabregas, David Silva and Michu.