London - Manchester City captain Vincent Kompany has been ruled out of Wednesday's Champions League tie at CSKA Moscow after failing to recover from a thigh injury.
Kompany missed Saturday's Premier League win at West Ham and Belgium's recent World Cup qualifiers after suffering the thigh problem against Everton earlier this month.
City manager Manuel Pellegrini said there was a possibility the 27-year-old defender could return to face the Russian champions this week, but he has now decided against the risk ahead of Sunday's trip to Chelsea.
Midfielder Jack Rodwell, who is reportedly fit again after overcoming his latest hamstring issue, has also not been included in the squad for the Group D fixture, but Spanish winger Jesus Navas, who was not involved at West Ham, has travelled for the crucial game.
After defeat to Bayern Munich last time out, City's hopes of reaching the knockout stages for the first time could hinge on their upcoming back-to-back matches against CSKA.
The two sides are level on three points, three behind Bayern, after recording victories over Viktoria Plzen but losing to the reigning champions.