Berlin - Borussia Dortmund's Germany striker Marco Reus has been ruled out of Friday's Euro 2016 qualifier against Gibraltar and the friendly away to Spain because of an ankle injury.
Dortmund's team doctor revealed that Reus suffered ligament damage and bruising to his left ankle during Sunday's 1-0 Bundesliga win over Moenchengladbach.
It is the second injury blow for Germany head coach Joachim Loew following that of Chelsea winger Andre Schuerrle.
The 24-year-old Schuerrle, whose extra-time cross led to Mario Goetze's winning goal for Germany in July's World Cup final, battled an infection last month and has told Loew he will stay in London to work on his fitness during the international break.
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Schuerrle last played in Germany's shock 2-0 defeat against Poland last month, but missed the 1-1 draw with Ireland due to illness. That result left Germany third in their Euro 2016 qualifying group with Poland top and Ireland second.
Reus, 25, missed Germany's World Cup triumph after suffering an ankle injury before their departure for Brazil.
He had been expected to return to the squad after missing the first three Euro 2016 qualifiers but injured his ankle again at the start of September.
Reus is expected to be back in action in two weeks.
The Germans' Euro 2016 qualifier against Gibraltar is in in Nuremburg on Friday before a prestigious friendly against Spain four days later in Vigo.